The eleven regular meetings of Beacon Angels in 2022 covered the following:
January 11, 2022
VeraMorph & Dyad Medical
Beacon Angels entertained the following presenters at its January 2022 meeting:
- VeraMorph: reformulating generic drugs to be more efficacious orally and co-developing new drugs through partnerships as a means to establish a diversified, low risk portfolio of therapeutics across a wide range of disease areas;
- Dyad Medical: developing AI-enabled clinical applications to assist cardiologists in the interpretation of medical images; and
We entertained a follow-on funding proposal from GelMEDIX, which is developing therapeutic drug-eluting gel capsules for the eye.
Members reported on current funding rounds, by Series number:
- S96, NF2 Therapeutics, developing a curative gene replacement therapy for the deafness, loss of mobility and devastating brain tumors caused by the NF2 orphan disease, and targeted antibody-drug conjugates to treat NF2-caused meningiomas.
Members delivered due diligence reports:
- Shoreline Biome (Zainulbhai, Doscher & Smith) developing and selling patent-protected assays for more accurate and comprehensive human microbiome testing and research;
- Jaia Robotics (Dave Smith) developing “JaiaBots,” low cost, high speed, micro-sized autonomous aquatic robots that work in pods of up to 20 to collect aquatic data from coastal waters up to 100m, estuaries, rivers, lakes and marshlands; and
- Imago Rehab (Michael Pietrasiewicz, Vicky Davis), providing a virtual clinic using telerehab supplemented by a robotic glove to facilitate daily, high-repetition rehabilitation to hand-impaired stroke patients.
February 8, 2022
TopProp Fantasy Sports & Encapsulate
At the Beacon meeting held on February 8, 2022, members entertained new company funding proposals from the following:
- TopProp Fantasy, offering a daily fantasy sports platform that simplifies DFS down to its core: single-player fantasy; and
- Encapsulate, which is develops an automated tumor-on-a-chip system to grow patient-derived microtumors, to screen them against a variety of chemotherapeutic drugs.
Members reported on the new company funding round of NF2 Therapeutics, together with that of Cognoptix, which raised $740K of a targeted $500-$700K convertible debt round to revamp and supplement the results of its most recent clinical trials.
Members delivered due diligence reports on the following companies:
- Dyad Medical, which is developing AI-enabled clinical applications to assist cardiologists in the interpretation of medical images;
- Jaia Robotics, developing “JaiaBots,” low-cost, high-speed, micro-sized autonomous aquatic robots that work in pods of up to 20 to collect aquatic data from coastal waters down to 100m, estuaries, rivers, lakes and marshlands; and
- Imago Rehab, providing a virtual clinic using telerehab supplemented by a robotic glove to facilitate daily, high-repetition rehabilitation to hand-impaired stroke patients
March 8, 2022
Contacts411 & Connective Health
At the Beacon Angels meeting on March 8, 2022, we entertained funding proposals from the following:
- Ryan Hess, of Contacts411, which provides contact data enhancement and updating for very small businesses; and
- Karen Sallick, of Connective Health, providing a SAAS platform to help primary care providers deliver behavioral healthcare (diagnosis and treatment of mental health, substance abuse, and associated physical disorders).
We discussed the funding rounds of Jaia Robotics, and Imago Rehab.
We discussed due diligence as to Dyad Medical, Shoreline Biome, TopProp Fantasy, and Encapsulate.
April 12, 2022
Pointz Mobility & The Family Learning Company
Beacon Angels entertained the following presenters at its April 2022 meeting:
- Pointz Mobility, a safety-focused mapping app that leverages crowdsourcing to help guide bike and scooter riders through pleasant, lower-stress routes in cities; and
- The Family Learning Company, creating literacy software that connects adult learners and their children.
We discussed the funding rounds of Jaia Robotics, and Imago Rehab.
We discussed due diligence reports as to Shoreline Biome, TopProp Fantasy, Encapsulate and Connective Health.
May 12, 2022
Bloom for All & OrderTaker Solutions
Beacon Angels members entertained funding proposals from the following new company presenters:
- BloomForAll (Joanne Mercaldi & Team), offering teenagers a safe, inclusive and mindful health information platform powered by doctors, educators, organizations, and social influencers; and
- OrderTaker Solutions (Amit Gathani), a Wholesale Distribution technology startup developing a mobile ordering app for field sales reps to engage in direct store delivery sales and increase sales revenues by at least 15-20%.
Members delivered a report on The New England Quarterly Summit of the Angel Capital Association held on May 4, 2022.
We heard member due diligence reports on the following:
- Pointz Mobility, a safety-focused mapping app that leverages crowdsourcing to help guide bike and scooter riders through pleasant, lower-stress routes in cities;
- Encapsulate, developing automated tumor-on-a-chip systems that can grow patients’ cancer cells and test the efficacy of cancer drugs; and
- Connective Health, disrupting behavioral health care.
June 14, 2022
Gynion, Idle Smart & Veramorph
Beacon Angels entertained the following presenters:
- Gynion—developing MenorrxTM treatment for Heavy Menstrual Bleeding (HMB), Menorrx is a safe and effective endometrial ablation therapy that is simpler, easier to use, and costs a fraction of the available alternatives;
- IdleSmart—offering a proprietary IoT solution for truck fleets to reduce yearly fuel costs of $10,000 per truck while increasing vehicle uptime and availability; and
- Veramorph, which reformulates generic drugs for oral efficacy and is co-developing a diverse portfolio of new drugs with a beachhead in the oral delivery of drug treatment for metastatic breast cancer.
There followed a due diligence report on Pointz Mobility, a safety-focused mapping app that leverages crowdsourcing to help guide bike and scooter riders through pleasant, lower-stress routes in cities.
Members reported on the funding rounds of:
- TopProp Fantasy, which has finalized the terms of its convertible note; and
- Imago Rehab, which has accepted an extension of BA Series 99’s investment.
July 12, 2022
RT Microfluidics & Alleviate Therapy
Beacon Angels entertained the following presenters at its July meeting:
- RT Microfluidics, which is developing a platform for saliva-based at-home diagnostics using molecular technologies; and
- Alleviate Therapy, which develops and sells self-treatment systems for chronic injuries, combining physical and digital technologies, with an initial focus on Plantar Fasciitis.
Beacon heard an update from portfolio company CEO David Bean, of Dermal Photonics, which develops effective and widely popular optical devices for the smoothing of facial wrinkles.
Members also reviewed current funding rounds:
- TopProp Fantasy, offering a daily fantasy sports platform that simplifies DFS down to its core: single-player fantasy; and
- Imago Rehab, offering remote hand therapy and rehabilitation to medical patients via a Web-linked robotic glove.
September 13, 2022
Skope & Passiva
Beacon Angels entertained the following presenters at its September 2022 meeting:
- Skope, offering a wall-mounted point-of-care bracket for the convenient and rapid disinfecting of the stethoscopes of medical service providers;
- Passiva PLT, developing the delivery by nanoparticle of passive phototherapy to transform the growth, healing and preventative capabilities of living things as an additive to everyday products; and
- (as a followup to a previous presentation) OrderTaker Solutions, a wholesale distribution technology startup developing a mobile ordering app for field sales reps to conduct direct store delivery sales to increase revenues by 15% or more.
Members discussed new funding rounds by the following, by Series number:
- S102 GelMEDIX developing gel-formulated drug delivery for the eye; and
- S103 Dermal Photonics, funding the sales and marketing of its new laser device.
October 11, 2022
FIND Neuro & QSM Diagnostics
Beacon Angels entertained the following presenters at its October meeting:
- FIND Neuro–employing proprietary neuronal dynamic algorithms to guide neurosurgeons in the treatment of Drug-Resistant Epilepsy;
- QSM Diagnostics–selling diagnostic mail-in kits and instruments to veterinarians to enable pet owners to collect samples and obtain diagnostic test results more quickly;
- In a follow-up, portfolio company NF2 Therapeutics reported on its clinical progress on both the ADC and genetic therapy fronts against its rare NF2 disease target; and
- In another follow-up, Lenoss Medical reported on its resumed progress toward approval of its device for surgeons to deliver internal support to crushed or weakened spinal vertebrae.
Members reported, by Series number, on the follow-on funding rounds of:
- S104 Diesel Labs, which continues building its platform for providing marketing feedback to streaming companies; and
- S105 IdleSmart, which offers intelligent truck idling management to save diesel fuel costs.
Members also reported on companies now in due diligence, Skope, Alleviate and Veramorph.
November 8, 2022
StageConnect & Mimosa
Beacon Angels entertained the following presenters at its November 2022 meeting:
- StageConnect (Cole Morgan), a two-way one-to-many video solution for live events that lets speakers see and interact with the faces of all live stream attendees in real-time; and
- Mimosa (possible, demonstration basis)(Karen Cross), developing subcutaneous skin imaging for wound early detection & treatment.
- For its follow-on round, Hilltop Biosciences, delivered an update on its developing and selling of new forms of wound care for veterinary use.
Members reported on the following companies now in due diligence:
- Skope, developing handy point-of-care sterilization for stethoscopes;
- Veramorph, reformulating generic drugs for oral efficacy with a bridgehead in the oral delivery of a standard therapy for metastatic breast cancer;
- QSM Diagnostics, selling diagnostic mail-in kits and instruments to veterinarians to enable pet owners to obtain diagnostic testing results faster; and
- MicroDX, developing a platform for saliva-based at-home diagnostics using molecular tech.
- Alleviate.
December 13th, 2022
Everyday Life & Stratagen Bio
- Everyday Life, in a repeat presentation, described how it is seizing the $40 billion opportunity to make life insurance accessible and affordable for middle-income families; and
- Stratagen Bio, which is enabling oxygen-guided personalized cancer therapies using proprietary innovations in materials science and MRI image acquisition and processing.
- In a portfolio company update, AOA Diagnostics described how it is bringing to market the first accurate early-stage non-invasive ovarian cancer diagnostic test; and in another,
- NF2 Therapeutics reported on its clinical success in developing orphan-disease treatments for the NF2 disease both on the ADC and the gene-therapy fronts.
Members reported on current funding rounds, by Series number.
- S86B Lenoss Medical;
- S96B NF2 Therapeutics;
- S106 Xeno; and
- S108 Hilltop Biosciences.
Members reported on the following companies now in due diligence:
- Skope, developing handy, point-of-care sterilization for stethoscopes;
- Veramorph, reformulating generic drugs for oral efficacy;
- QSM Diagnostics, offering diagnostic mail-in kits and instruments to veterinarians to enable pet owners to obtain diagnostic testing results faster;
- MicroDX, developing a platform for saliva-based at-home diagnostics and
- StageConnect, which is developing a platform to support large, corporate-wide remote meetings.